In 2003, David Smith weighed 630 lbs.
In 2007, before he had excess skin removed, he weighed 229 lbs. 401 lbs lost.
So far, in two surgeries (he'll have 3 total), 22.5 lbs of skin have been removed.
A couple of videos:
For my part, I'm down to 287, and am wearing pants with a 40" waist. Today I buttoned and zipped a pair of size 38 pants. I couldn't breath, but did button them!